The lens is held in its normal position behind the iris and pupil by tiny strands called "zonules". Disruption of the zonules can cause the lens to move out of its normal position (luxate). When a lens is only partially held by some zonules, it is referred to as a subluxated lens. When a lens is no longer held by any zonules, it is called a luxated lens. Two general categories of lens luxation are defined according to whether or not the luxation was the first eye problem (primary lens luxation) or whether it was caused by another eye condition (secondary lens luxation). Primary lens luxation is seen more commonly in certain breeds where the defective lens zonules weaken and break over time. Trauma to the eye or head can also cause lens luxation, although it is not usually the primary cause. Trauma severe enough to cause lens luxation usually also causes other obvious eye problems.
Lens luxation is known to be an inherited condition in many breeds. The mechanism of inheritance has not been defined in most of these breeds. Dogs affected with the condition should not be used for breeding as this is the only way to remove the defect from the genetic pool. Yearly eye exam is highly recommended conc. dogs used for breeding.
A list of the PRA/LL affected, diganosed Tibetan Terriers can be found on the Tibetan Terrier International site. |